Key Publications: Michaela Fenckova

Michaela Fenckova

Key Publications

1: Fenckova M*¶, Muha V*, Mariappa D*, Catinozzi M, Czajewski I, Blok LER, Ferenbach AT, Storkebaum E, Schenck A, van Aalten DMF¶. Intellectual disability-associated disruption of O-GlcNAc cycling impairs habituation learning in Drosophila. PLoS Genet. 2022 May 2;18(5):e1010159. doi: 10.1371/journal.pgen.1010159. eCollection 2022 May. * Shared first authors ; ¶ Corresponding author 

2: Riahi H, Fenckova M, Goruk KJ, Schenck A, Kramer JM. The epigenetic regulator G9a attenuates stress-induced resistance and metabolic transcriptional programs across different stressors and species. BMC Biol. 2021 May 24;19(1):112. doi: 10.1186/s12915-021-01025-0.

3: Muha V*, Fenckova M*, Ferenbach AT, Catinozzi M, Eidhof I, Storkebaum E, Schenck A, van Aalten DMF. O-GlcNAcase contributes to cognitive function in Drosophila. J Biol Chem. 2020 Feb 24: jbc.RA119.010312. doi: 10.1074/jbc.RA119.010312. * Shared first authors 

4: Fenckova M, Blok LER, Asztalos L, Goodman DP, Cizek P, Singgih EL, Glennon JC, IntHout J, Zweier C, Eichler EE et al. Habituation Learning Is a Widely Affected Mechanism in Drosophila Models of Intellectual Disability and Autism Spectrum Disorders. Biol Psychiatry. 2019 Aug 15;86(4):294-305. doi: 10.1016/j.biopsych.2019.04.029. Epub 2019 May 9. 

5: Stessman HA, Xiong B, Coe BP, Wang T, Hoekzema K, Fenckova M, Kvarnung M, Gerdts J, Trinh S,  Cosemans N et al. Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases. Nat Genet. 2017 Apr;49(4):515-526. doi: 10.1038/ng.3792. Epub 2017 Feb 13. 

6: Lugtenberg D*, Reijnders MRF*, Fenckova M*, Bijlsma EK, Bernier R, B. van Bon WM, Smeets M, Vulto-van Silfhout AT, Bosch D, Eichler EE et al. De novo loss-of-function mutations in WAC cause a recognizable intellectual disability syndrome and learning deficits in Drosophila. Eur J Hum Genet. 2016 Jan 13. doi: 10.1038/ejhg.2015.282.  * Shared first authors 

7: Esmaeeli-Nieh S*, Fenckova M*, Porter IM*, Motazacker MM, Nijhof B, Castells Nobau A, Asztalos Z, Weißmann R, Behjati F, Tzschach A et al. BOD1 is required for cognitive function in human and Drosophila. PLoS Genet. 2016 May 11;12(5):e1006022. doi: 10.1371/journal.pgen.1006022. eCollection 2016 May.  *Shared first authors 

8: Kochinke K, Zweier Ch, Nijhof B, Fenckova M, Cizek P, Honti F, Keerthikumar S, Oortveld MAW, Kleefstra T, Kramer JM et al.  Systematic Phenomics Analysis Deconvolutes Genes Mutated in Intellectual Disability into Biologically Coherent Modules. Am J Hum Genet.2016 doi: 10.1016/j.ajhg.2015.11.024. 

9: Lotan A*, Fenckova M*¶, Bralten J, Alttoa A, Dixson L, Williams RW, van der Voet M. Neuroinformatic analyses of common and distinct genetic components associated with major neuropsychiatric disorders. Front Neurosci. 2014 Nov 6;8:331. eCollection. * Shared first authors  ¶ Corresponding author.